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Hemp Oil For Inflammation – Studies Show Benefits of Cannabinoids

Research shows cannabinoids can stop inflammation by activating CB2 receptors found in the endocannabinoid system.

A couple of years ago, a study comparing the levels of inflammation in people who smoked marijuana and in people who never smoked it was showing that marijuana smokers may have lower levels of inflammation. Data from 9,000 people was examined in the mentioned study, researchers analyzing the influence of marijuana on the levels of C-reactive protein (CRP), a marker of inflammation that is frequently linked with an increased risk of heart disease.

Hemp Oil For InflammationChronic inflammation also plays a role in autoimmune diseases like arthritis, lupus, colitis or multiple sclerosis, so researchers wanted to see whether the active components in marijuana can decrease the levels of CRP, reducing inflammation. 12% of study participants said they smoked marijuana recently, and researchers found that people who smoked in the past 30 days had lower levels of C-reactive protein than those who had never smoked marijuana.

Hemp Oil For Inflammation Using Cannabinoids

These findings weren’t a surprise, as cannabis has been long recognized as a medicinal plant, and there are several studies that prove the effectiveness of cannabinoids in decreasing inflammation. Here’s one study from researchers at the University of South Carolina for example, which showed that THC has the capacity to affect DNA expression in a manner that may lead to suppression of inflammation.

As explained in a previous article, THC is the compound in the cannabis plant responsible for its psychoactive effect. Because THC makes you “high”, it’s often regarded as a harmful component of the Cannabis sativa plant, but this perception is not an objective one, as THC has its positive effects as well.

The other powerful component in cannabis, CBD, was also proven to reduce inflammation and is thought to play a role in the treatment of arthritis symptoms. According to researchers at the Imperial College London, hemp oil for inflammation  CBD (cannabidiol) can reduce inflammation in mice by 50% at the right dosage, and can fight against type 1 diabetes. Also, research done by G.W.Pharmaceuticals showed that CBD could be used for treating rheumatoid arthritis symptoms, as well as diabetes, bowel disorders or nausea.

Of all the compounds in the Cannabis sativa plant, the ones that play a role in inhibiting inflammation are the substances that activate the CB2 receptors. As you know, the CB2 receptors are part of the endocanabinoid system along with CB1 receptors, the first ones being found in the central nervous system and influencing perception, memory, mood, sleep and appetite, while CB2 receptors are involved in immunity.

Cannabidiol (CBD) is not the only compound in cannabis that activates the CB2 receptor. Another substance called beta-carophyllene also activates this receptor, and has no psychoactive effect. According to scientists from ETH Zurich and Bonn University, this substance may help not only in stopping inflammation but also in preventing or treating ailments like liver cirrhosis, osteoarthritis or arteriosclerosis.

Here’s even more proof that hemp oil for inflammation and cannabinoids can help in reducing inflammation:

  • A study published in the Free radical biology & medicine journal by US researcher G.W. Booz from the University of Mississippi Medical Center showed that cannabidiol can be helpful in lessening the impact of inflammation on oxidative stress, decreasing the risk of organ damage and dysfunction. Oxidative stress and inflammation contribute to a number of diseases, such as rheumatoid arthritis, diabetes type 1 and 2, atherosclerosis, hypertension, metabolic syndrome, Alzheimer’s disease or depression.
  • Scientists from the National Institutes of Health, Bethesda (US) showed that cannabinoids can suppress inflammatory and neuropathic pain without causing analgesic tolerance.
  • Cannabinoids suppress inflammatory response and attenuate disease symptoms by inducing apoptosis in activated immune cells, suppressing cytokines and chemokines at inflammatory sites and upregulating FoxP3+ regulatory T cells.

Have something to add to this article? Comment below, and if you want to learn more about the beneficial health effects of cannabinoids and about the endocannabinoid system, check our blog regularly for updates.

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Join the discussion 8 Comments

  • Morag Mackay says:

    This article is 100% correct – out of the mouth of God. I have been using Elixinol CBD Rich hemp oil since October last year and have pain-free days and a new lease on life. I suffer from a rare spinal nerve disorder called syringomyelia and without this oil a dark hole was my refuge but no longer. The only holes I go into now are full of sunshine.

  • It’s interesting that the oil has some key elements that could help reduce inflammation. My wife has been dealing arthritis, and we are looking at different ways it could potentially be helped. I’ll have to keep this in mind as it gets more popular to see the route that the oil takes.

  • […] with cannabinoids and their health effects.  In a previous article, we’ve detailed the anti-inflammatory action of these substances, so now it’s time to discuss about the use of CBD and THC in the […]

  • I had no idea that hemp oil could help with inflammation. I have been wondering about hemp oil for quite some time. I normally just eat hemp hearts because those are healthy. You have convinced me of this oil’s usefulness.

  • Kaitlyn says:

    This was an interesting read! Many suffer from arthritis symptoms, hemp oil seems like a really good solution.

  • Suzie says:

    Very informative article! I have had Rgeumatoid Arthritis for almost 2 years. It is worsening and getting extremely painful. I refuse to use “biologics” due to the side effects, but all the other medicine is really just as bad. I have been looking for a natural remedy, and I think I may have just found it. I am over the pain and sleepless nights; the never ending flare that gets worse with weather and pressure changes. I plan on trying this, hopefully it had a positive effect!

    • Linda says:

      I am with you on this!! I have several painful arthritic related problems, REFUSED BigbPharm and side effects. i get lumbar injections, but 3 months between them gets very painful. I work part time in a library, my jobs physical.

  • darlene cook says:

    will hemp oil help pain of fibromaylasia?

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